Do you have trouble with the same people–sign wise? I am thinking that I do. If you have someone who gets under your skin, make a note of his or her Sun sign, as that is, usually, obvious. If you know Astrology, try to find the Moon sign. These would be the two biggest players in a person annoying you. The Ascendant does not seem as strong, here. The Ascendant is not as much of a “built in” position, as the Sun and the Moon. The Ascendant is a position in space, not an actual planetary body. That may be the reason.
At any rate, the people who annoy me seem to have Aquarius Suns and Virgo moons. The Aquarius Sun is the number one irritant Sun sign, for me. I have gone to my chart to see why the Aquarius Sun would be the one which bothers me, the most. I have floated theories on which signs annoy people, based on one’s chart.
I have not gotten conclusive answers. I think that the sign of your Chiron may be a factor. Mine is in Aquarius. My mother’s Sun is an exact conjunction with my Chiron, in the 4th House. My mother has an Aqua Sun with an exact conjunction( combust) with her Aquarius mercury. This conjuncts my Chiron. Maybe, this is the reason for my dislike of Aquarius Suns.
PS To my sweet friends with Aquarius Suns, this is not meant for you!